Our aim was to study the selected cases of the patients with ischemic heart disease\nand to analyze the structure of blood serum of patients in comparison with control\nserum of healthy subjects by methods: synchronous fluorescence fingerprint and\natomic force microscopy that are still not used in clinical practice. Our results of fluorescence\nanalysis showed that blood serum of all patients with ischemic heart disease\ndecreased intensity of fluorescence in comparison with control blood serum.\nEndogenous fluorescence of synchronous fluorescence fingerprint of blood serum of\npatients with unstable angina pectoris state after non ST elevation myocardial infarction;\nangina pectoris and arterial hypertension 3 was similar, but atomic force microscopy\nrevealed differences in the structure of blood serum of patients with the angina\npectoris. Blood serum of patients with angina pectoris exhibited disappearance\nof fluorescence peak with maximum fluorescence and showed lower fluorescence intensity\nthan control blood serum and blood serum of patients with arterial hypertension\n2. Profiles of synchronous fluorescence fingerprint of blood serum of patients\nwith arterial hypertension stage 2 showed formation of the new fluorescent peak with\nmaximum fluorescence, similar shape of synchronous fluorescence fingerprint and\nhigher fluorescence intensity than blood serum of healthy subjects. Blood serum sensitively\nrevealed changes in the body by using untraditional novel techniques which\nenable the analysis of the mixture of blood serum and might be a new possibility in\nstudy of heart ischemia diseases.
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